Research

Meta-analyses

Trials, meta-analyses, and systematic reviews indexed in PubMed, newest first. Each entry links to the original record and to the treatments it covers.

Index updated Oct 13, 2026

All studies Randomized trials Meta-analyses Systematic reviews

59 studies

Meta-analysis

Systematic Review and Meta-Analysis: Plant-Based Therapy for Irritable Bowel Syndrome.

Meyer A, Auer J, et al.

Phytother ResOct 2026

Meta-analysis

Assessing the Efficacy of Functional Food as Treatment for Irritable Bowel Syndrome with Constipation: A Systematic Review and Network Meta-Analysis.

Mou J, Xu L, et al.

Nutr RevAug 2026

Meta-analysis

Characteristics and clinical applicability of four dietary interventions for irritable bowel syndrome: A systematic review and meta-analysis.

Yang X, Shui X

Clin NutrJul 2026

Meta-analysis

Efficacy and Safety of Postbiotics in Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis.

Ayad ME, Yu S, et al.

J Gastroenterol HepatolJul 2026

Meta-analysis

Efficacy of Internet-Based Self-Help Interventions for Irritable Bowel Syndrome: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Xu X, Liu T, et al.

J Med Internet ResMay 2026

Meta-analysis

Probiotics for Irritable Bowel Syndrome: An Updated Systematic Review and Meta-Analysis With Trial Sequential Analysis.

Probiotics

Tang ASP, Quek J, et al.

J Gastroenterol HepatolApr 2026

Meta-analysis

Serological and faecal markers of irritable bowel syndrome: a systematic review and meta-analysis.

Burns GL, Roberts F, et al.

EBioMedicineApr 2026

Meta-analysis

Effect of multistrain probiotics on symptom severity in irritable bowel syndrome: a systematic review and meta-analysis of irritable bowel syndrome-symptom severity score outcomes.

Probiotics

Anwar DFF, Salma ZN, et al.

Eur J Gastroenterol HepatolApr 2026

Meta-analysis

Efficacy of hypnotherapy in the treatment of irritable bowel syndrome (IBS): A systematic review and meta-analysis.

Hypnotherapy

Almogbel E, A Al-Harbi F, et al.

Am J Clin HypnMar 2026

Meta-analysis

The effects of different exercise interventions on clinical outcomes of irritable bowel syndrome and their potential mechanisms: a systematic review and network meta-analysis.

Exercise

Quan Z, Song W, et al.

Front ImmunolFeb 2026

Meta-analysis

Efficacy of Tongxie Yaofang compared with pinaverium bromide on irritable bowel syndrome with liver depression and spleen deficiency: a systematic review and Meta-analysis.

Mi Z, Huaien BU, et al.

J Tradit Chin MedFeb 2026

Meta-analysis

Face-to-Face Versus Digital, Telephone-Delivered, and Self-Help Cognitive Behavioral Therapy for Irritable Bowel Syndrome: Systematic Review and Bayesian Indirect Treatment Comparison Meta-Analysis.

Tao QF, Hua C, et al.

J Med Internet ResJan 2026

Meta-analysis

Does amitriptyline help for irritable bowel syndrome pain management?: An updated systematic review and meta-analysis.

Alhajaji R, Alfahmi M, et al.

Medicine (Baltimore)Jan 2026

Meta-analysis

Efficacy and safety of interventions for Fibromyalgia syndrome comorbid with Irritable bowel syndrome: systematic review.

Elkalla MA, Ali YG, et al.

Clin RheumatolJan 2026

Meta-analysis

Comparative effectiveness and safety of probiotics with psychotropic potential in mental health benefits in irritable bowel syndrome: a systematic review and network meta-analysis.

Probiotics

Rokkas T, Ekmektzoglou K, et al.

Eur J Gastroenterol HepatolJan 2026

Meta-analysis

Efficacy of Specific Probiotic Strains in Subtypes of Irritable Bowel Syndrome: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Probiotics

Almalki AS, Jaafari NY, et al.

Medicina (Kaunas)Dec 2025

Meta-analysis

Efficacy of behavioural therapies for irritable bowel syndrome: a systematic review and network meta-analysis.

Thakur ER, Khasawneh M, et al.

Lancet Gastroenterol HepatolDec 2025

Meta-analysis

Yoga for Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Exercise

Saab O, Al-Obaidi H, et al.

Am J GastroenterolDec 2025

Meta-analysis

Effects of Probiotics and Diet Management in Patients With Irritable Bowel Syndrome: A Systematic Review and Network Meta-analysis.

Probiotics

Lei Y, Sun X, et al.

Nutr RevSep 2025

Meta-analysis

Impacts of the Long-Term Low-FODMAP Diet in Patients With Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis.

Low FODMAP

Pouladi A, Arabpour E, et al.

J Hum Nutr DietAug 2025

Meta-analysis

Gut-Directed Hypnotherapy for Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis.

Hypnotherapy

Adler EC, Levine EH, et al.

Neurogastroenterol MotilJul 2025

Meta-analysis

Impact of vitamin D supplementation on symptom severity and quality of life in patients with irritable bowel syndrome: A meta-analysis.

Vitamin D

Qi S, Zhao M, et al.

Adv Clin Exp MedJul 2025

Meta-analysis

Efficacy of dietary interventions in irritable bowel syndrome: a systematic review and network meta-analysis.

Cuffe MS, Staudacher HM, et al.

Lancet Gastroenterol HepatolJun 2025

Meta-analysis

Efficacy of interventions for the treatment of irritable bowel syndrome, functional abdominal pain-not otherwise specified, and abdominal migraine in children: a systematic review and network meta-analysis.

Sinopoulou V, Groen J, et al.

Lancet Child Adolesc HealthMay 2025

Meta-analysis

Probiotics Combined With Trimebutine for the Treatment of Irritable Bowel Syndrome Patients: A Systematic Review and Meta-Analysis.

Probiotics

Yu QX, Wang DD, et al.

J Gastroenterol HepatolMar 2025

Meta-analysis

The effects of vitamin D intake and status on symptom severity and quality-of-life in adults with irritable bowel syndrome (IBS): a systematic review and meta-analysis.

Vitamin D

Cara KC, Taylor SF, et al.

Crit Rev Food Sci NutrJan 2025

Meta-analysis

Efficacy and Safety of a Low-FODMAP Diet in Combination with a Gluten-Free Diet for Adult Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis.

Zhang J, Yu P, et al.

Dig Dis SciNov 2024

Meta-analysis

Effect of Brain-Gut Behavioral Treatments on Abdominal Pain in Irritable Bowel Syndrome: Systematic Review and Network Meta-Analysis.

Goodoory VC, Khasawneh M, et al.

GastroenterologyOct 2024

Meta-analysis

The Efficacy of Probiotics, Prebiotics, Synbiotics, and Fecal Microbiota Transplantation in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis.

Wu Y, Li Y, et al.

NutrientsJul 2024

Meta-analysis

The efficacy and real-world effectiveness of a diet low in fermentable oligo-, di-, monosaccharides and polyols in irritable bowel syndrome: A systematic review and meta-analysis.

Low FODMAP

Jent S, Bez NS, et al.

Clin NutrJun 2024

Meta-analysis

Effects of a low FODMAP diet on the symptom management of patients with irritable bowel syndrome: a systematic umbrella review with the meta-analysis of clinical trials.

Low FODMAP

Khalighi Sikaroudi M, Soltani S, et al.

Food FunctMay 2024

Meta-analysis

Efficacy and safety of probiotics in irritable bowel syndrome: A systematic review and meta-analysis.

Probiotics

Yang R, Jiang J, et al.

Clin Nutr ESPENApr 2024

Meta-analysis

Frequency of irritable bowel syndrome in spondyloarthritis: a multicentric cross-sectional study and meta-analysis.

Bernard J, Barnetche T, et al.

RMD OpenJan 2024

Meta-analysis

A systematic review and meta-analysis of diet and nutrient intake in adults with irritable bowel syndrome.

Veraza DI, Calderon G, et al.

Neurogastroenterol MotilJan 2024

Meta-analysis

Different therapies of Chinese herbal medicine for diarrhea-predominant irritable bowel syndrome: A network meta-analysis of double-blinded, placebo-controlled trials.

Liu N, Li J, et al.

J EthnopharmacolDec 2023

Meta-analysis

Probiotics for the management of irritable bowel syndrome: a systematic review and three-level meta-analysis.

Probiotics

Chen M, Yuan L, et al.

Int J SurgNov 2023

Meta-analysis

Efficacy of Probiotics in Irritable Bowel Syndrome: Systematic Review and Meta-analysis.

Probiotics

Goodoory VC, Khasawneh M, et al.

GastroenterologyNov 2023

Meta-analysis

Psychological treatments for irritable bowel syndrome: a comprehensive systematic review and meta-analysis.

Axelsson E, Kern D, et al.

Cogn Behav TherNov 2023

Meta-analysis

Systematic review with meta-analysis: effects of probiotic fungi on irritable bowel syndrome.

Probiotics

Qing Q, Chen Y, et al.

Benef MicrobesSep 2023

Meta-analysis

Outcome-Specific Efficacy of Different Probiotic Strains and Mixtures in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis.

Probiotics

Xie P, Luo M, et al.

NutrientsSep 2023

Meta-analysis

Efficacy of probiotics, prebiotics and synbiotics in irritable bowel syndrome: a systematic review and meta-analysis of randomized, double-blind, placebo-controlled trials.

Zhang WX, Shi LB, et al.

J Med MicrobiolSep 2023

Meta-analysis

Efficacy and safety of probiotics in the treatment of irritable bowel syndrome: A systematic review and meta-analysis of randomised clinical trials using ROME IV criteria.

Probiotics

Konstantis G, Efstathiou S, et al.

Clin NutrMay 2023

Meta-analysis

The efficacy of exogenous melatonin supplement in ameliorating irritable bowel syndrome severity: A meta-analysis of randomized controlled trials.

Melatonin

Chen KH, Zeng BY, et al.

J Formos Med AssocMar 2023

Meta-analysis

Probiotics therapy for adults with diarrhea-predominant irritable bowel syndrome: a systematic review and meta-analysis of 10 RCTs.

Probiotics

Wang Y, Chen N, et al.

Int J Colorectal DisNov 2022

Meta-analysis

Prevalence and Influencing Factors of Irritable Bowel Syndrome in Medical Staff: A Meta-Analysis.

Liu H, Zou Y, et al.

Dig Dis SciNov 2022

Meta-analysis

Vitamin D status in irritable bowel syndrome and the impact of supplementation on symptoms: a systematic review and meta-analysis.

Vitamin D

Bin Y, Kang L, et al.

Nutr HospOct 2022

Meta-analysis

Effects of a low FODMAP diet on the colonic microbiome in irritable bowel syndrome: a systematic review with meta-analysis.

Low FODMAP

So D, Loughman A, et al.

Am J Clin NutrOct 2022

Meta-analysis

Systematic review and meta-analysis: efficacy of peppermint oil in irritable bowel syndrome.

Peppermint oil

Ingrosso MR, Ianiro G, et al.

Aliment Pharmacol TherSep 2022

Meta-analysis

Comparing probiotic and drug interventions in irritable bowel syndrome: a meta-analysis of randomised controlled trials.

Probiotics

van der Geest AM, Schukking I, et al.

Benef MicrobesAug 2022

Meta-analysis

Efficacy of a Restrictive Diet in Irritable Bowel Syndrome: A Systematic Review and Network Meta-analysis.

Yu SJ, Lee HS, et al.

Korean J GastroenterolJul 2022

Meta-analysis

Physical activity for treatment of irritable bowel syndrome.

Exercise

Nunan D, Cai T, et al.

Cochrane Database Syst RevJun 2022

Meta-analysis

The Effect of Vitamin D Supplementation on the Severity of Symptoms and the Quality of Life in Irritable Bowel Syndrome Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Vitamin D

Abuelazm M, Muhammad S, et al.

NutrientsJun 2022

Meta-analysis

Effectiveness and Safety of Probiotics for Patients with Constipation-Predominant Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis of 10 Randomized Controlled Trials.

Probiotics

Shang X, E FF, et al.

NutrientsJun 2022

Meta-analysis

Internet-Delivered Cognitive Behavioral Therapy in Patients With Irritable Bowel Syndrome: Systematic Review and Meta-Analysis.

Kim H, Oh Y, et al.

J Med Internet ResJun 2022

Meta-analysis

Vitamin D supplementation for irritable bowel syndrome: A systematic review and meta-analysis.

Vitamin D

Chong RIH, Yaow CYL, et al.

J Gastroenterol HepatolJun 2022

Meta-analysis

Efficacy of a low FODMAP diet in irritable bowel syndrome: systematic review and network meta-analysis.

Low FODMAP

Black CJ, Staudacher HM, et al.

GutJun 2022

Meta-analysis

The efficacy of vitamin D supplementation for irritable bowel syndrome: a systematic review with meta-analysis.

Vitamin D

Huang H, Lu L, et al.

Nutr JMay 2022

Meta-analysis

Effects of probiotic supplementation on abdominal pain severity in pediatric patients with irritable bowel syndrome: a systematic review and meta-analysis of randomized clinical trials.

Probiotics

Fatahi S, Hosseini A, et al.

World J PediatrMay 2022

Meta-analysis

Efficacy of Probiotics for Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis.

Probiotics

Zhang T, Zhang C, et al.

Front Cell Infect MicrobiolApr 2022