IBS in the news

Bowel cancer “melted away” after immunotherapy, then stayed away

A short course of immunotherapy before surgery may offer remarkably durable protection for some patients with stage two or three bowel cancer.

Successful Engraftment Without Relief: Closing the Chapter on Fecal Microbiota Transplantation in IBS?

Real-time abdominal pain – daily life trigger associations in IBS: a multicenter Experience Sampling Method Study

Gastrointestinal symptoms in irritable bowel syndrome (IBS) are influenced by daily life triggers.

Easing constipation: A 20-minute walk can get your gut moving almost immediately

Researchers found that just 20 minutes of comfortable walking can rapidly stimulate the gut. Within one to two minutes after exercise, bowel sounds became…

• Exercise

Blue Notes

Irritable bowel syndrome (IBS) is associated with sex- and gender-related differences in prevalence and clinical presentation.

Blood tests reveal why astronauts get constipated in space

Spaceflight may dramatically change the gut within weeks, causing bacteria to break down more protein as food moves more slowly through the intestines.

Managing IBS-Like Symptoms in Quiescent Inflammatory Bowel Disease: A Meta-Analysis of Randomized Trials.

Persistent IBS-like symptoms affect up to one-third of patients with inflammatory bowel disease (IBD) in remission, representing a major unmet need not…

From Gut to Brain: Integrating Gastropsychology Training Into Gastroenterology Fellowship

1 These conditions, including irritable bowel syndrome, functional dyspepsia, and other disorders of gut–brain interaction, generate substantial health care…

Letter to the Editor Re: A Randomized Trial of Rifaximin vs Low FODMAP Diet

We read with interest the report by Lee and colleagues.

• Low FODMAP

Reply

1 We acknowledge that the modest sample size, single-center setting, and open-label design limit definitive conclusions.

Study of 1.9 million people finds a striking link between ADHD and gut problems

9 million people found that ADHD is associated with substantially higher rates of digestive problems. People with ADHD had nearly double the odds of…

Foodborne Illnesses can Lead to Long-Term Gut Issues

Foodborne Illnesses Can Lead to Long-Term Gut Issues A recent New York Times article explores post-infection irritable bowel syndrome (PI-IBS), a condition in…

Should We Abandon Nortriptyline for Functional Dyspepsia? Lessons From the TENDER Trial

1 By integrating CYP2D6-guided patient selection with plasma nortriptyline measurements, the study supports the development of a more personalized approach to…

Individualized Targeted Exclusion Diet Based on Confocal Laser Endomicroscopy Does Not Improve Irritable Bowel Syndrome Symptoms: A Randomized Controlled Crossover Trial

In patients with irritable bowel syndrome, real-time microscopic changes in the small intestine after food administration were not useful to tailor an…

A Single Question on Quality-of-Life Improvement Identifies Treatment Satisfaction in Irritable Bowel Syndrome

1-3 Although multiple pharmacologic therapies are available, the treatment benefit seen in routine practice may differ from the outcomes observed in randomized…

Diagnostic Performance of the Nine-Item Avoidant/Restrictive Food Intake Disorder Screen in Patients With Disorders of Gut–Brain Interaction

2–4 Although the NIAS has been validated in eating disorder populations, its performance characteristics for identifying ARFID in patients with DGBI remains…

End Point Discordance in Irritable Bowel Syndrome With Constipation: Bloating as a Partially Uncaptured Therapeutic Signal

Abdominal bloating adversely affects most individuals with constipation-predominant irritable bowel syndrome (IBS-C), frequently prompting them to seek care.

This common vitamin deficiency becomes far more dangerous when paired with belly fat

A large study of more than 5,500 adults over 50 found a striking combination of risk factors: abdominal obesity paired with vitamin D deficiency was linked to…

• Vitamin D

Fiber Supplementation in Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Fiber supplements lead to clinical response in irritable bowel syndrome, with psyllium most effective. More research is needed to understand which fibers might…

• Soluble fiber

Rome Foundation Releases Key Data on Worldwide Prevalence & Burden of DGBI

Rome Foundation Releases Key Data on Worldwide Prevalence & Burden of Disorders of both adult and pediatric Gut-Brain Interaction, according to the new Rome V…

Managing Complex Irritable Bowel Syndrome: A Multidisciplinary, Mechanism-Based Approach

After obtaining the patient’s consent, this clinical case was discussed in a multidisciplinary panel consisting of an adult gastroenterologist (AL), a…

Rice bran compound may help ease irritable bowel symptoms

A compound in rice bran may help calm an overactive gut by reducing the calcium signals that cause intestinal muscles to contract. Ferulic acid suppressed…

• Soluble fiber

Epidemiologic, Clinical, and Psychological Characteristics of Individuals With Self-Reported Irritable Bowel Syndrome Based on the Rome V vs Rome IV Criteria

The Rome V process altered diagnostic criteria for irritable bowel syndrome (IBS) compared with Rome IV, by modifying the requirement for frequency and…

Concern Regarding the Events-per-Variable Ratio in a Persistence Analysis of Irritable Bowel Syndrome

1 The analysis, as presented in Figure 1, appears to include up to 27 exposure variables in the model. However, it is based on only 50 persistence cases of IBS…