Trial · NCT06757491
Lf-rTMS Attenuates Visceral Pain in Irritable Bowel Syndrome With Diarrhea
Objectives: To identify a central hub of visceral pain in IBS-D and elucidate the mechanism by which repetitive transcranial magnetic stimulation (rTMS) confers
- Status
- Recruiting
- Sponsor
- The First Affiliated Hospital of Soochow University
- Study type
- Interventional
- Phase
- No phase
- Enrollment
- 42 participants (planned)
- Start
- Aug 1, 2024
- Primary completion
- Dec 25, 2025
- Conditions
- Repetitive Transcranial Magnetic Stimulation, Chronic Visceral Pain, Functional Magnetic Resonance Imaging, IBS (Irritable Bowel Syndrome), Clinical Efficacy
Summary
Objectives: To identify a central hub of visceral pain in IBS-D and elucidate the mechanism by which repetitive transcranial magnetic stimulation (rTMS) confers analgesic effects. Methods: A total of 42 IBS-D patients were recruited and randomly assigned (1:1) to the sham rTMS or the rTMS group. A nested cohort of 21 IBS-D participants who completed baseline fMRI assessments prior to randomization was included. Consistent with the randomization procedure，these individuals were evenly distributed between the two groups.
Interventions
- Repetitive Transcranial Magnetic Stimulation Device
- Sham (No Treatment) Device
Locations
1 country: China.
| Facility | City | Country |
|---|---|---|
| The First Affiliated Hospital of Soochow University | Suzhou, Jiangsu | China |
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