Trial · NCT05120752
Efficacy of a Low FODMAP Diet in the Absence of Lactose Malabsorption in Moderate to Severe ROME IV IBS.
Irritable bowel syndrome (IBS) is a frequently encountered disorder. According to the Rome IV criteria, it is characterized by abdominal pain associated with a
- Status
- Recruiting
- Sponsor
- Universitair Ziekenhuis Brussel
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 60 participants (planned)
- Start
- Nov 2, 2021
- Primary completion
- January 2028
- Conditions
- Irritable Bowel Syndrome
Summary
Irritable bowel syndrome (IBS) is a frequently encountered disorder. According to the Rome IV criteria, it is characterized by abdominal pain associated with a change in stool frequency or con-sistency, or with symptomatic improvement by defecation (Mearin 2016). Associated symptoms, such as bloating and flatulence, are frequently reported. The underlying pathophysiology remains obscure, although several pathways have been proposed. Low-grade immune activation, visceral hypersensitivity, alteration in gut microbiome have all been reported (Mearin 2016).
Interventions
- FODMAP diet Other
Locations
1 country: Belgium.
| Facility | City | Country |
|---|---|---|
| UZ Brussel | Jette, Brussels Capital | Belgium |
TreatIBS is an informational site and does not provide medical advice. The research summarized here may not apply to your situation. Talk with a clinician before starting, stopping, or changing any treatment.
Listing only. Eligibility is decided by the study team. TreatIBS is not involved in recruitment.